Structure-activity relationships for the 9-(pyridin-2'-yl)- aminoacridines.
نویسندگان
چکیده
A series of 9-(pyridin-2'-yl)-aminoacridines was prepared and analyzed for their ability to change the thermal denaturation temperature of genomic calf thymus DNA. Development of a QSAR equation indicated that electron withdrawing groups on the pyridine ring promoted the interaction with double stranded DNA.
منابع مشابه
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ورودعنوان ژورنال:
- Molecules
دوره 9 3 شماره
صفحات -
تاریخ انتشار 2004